Gerard A. Ateshian

Andrew Walz Professor and Chair of Mechanical Engineering & Professor of Biomedical Engineering
Columbia University, Department of Mechanical Engineering, 500 W 120th St, MC4703, 220 SW Mudd, New York, NY 10027
+1 212 854 8602
+1 212 854 3304

Education

  • B.S. Columbia University, Mechanical Engineering, 1986
  • M.S. Columbia University, Mechanical Engineering, 1987
  • M.Phil. Columbia University, Mechanical Engineering, 1990
  • Ph.D. Columbia University, Mechanical Engineering, 1991

Active Areas of Research

  • Theoretical and experimental analysis of articular cartilage mechanics
  • Theoretical and experimental analysis of cartilage lubrication
  • Cartilage tissue engineering and bioreactor design
  • Growth and remodeling of biological tissues
  • Cell mechanics
  • Mixture theory for biological tissues: Theory, experiments, and computational analysis

Past Areas of Research

  • Stereophotogrammetry, magnetic resonance imaging, and computed tomography techniques for reconstruction of musculoskeletal anatomy
  • Geometric modeling, surface-fitting, and curvature analysis of diarthrodial joint articular surfaces
  • Experimental determination of diarthrodial joint kinematics and contact
  • Modeling of diarthrodial joints
  • Biomechanics of the knee, shoulder, and hand
  • Computer-aided surgical planning

Gerard Ateshian's research combines theoretical, computational, and experimental methods to address the biomechanics of biological soft tissues and cells. His initial focus of research addressed the biomechanics of diarthrodial joints, including the measurement and analysis of their kinematics and contact mechanics, and the quantitative assessment of articular surface topgraphy and cartilage thickness. These studies were followed by the investigation of cartilage mechanics, with a focus on the disparity between the tensile and compressive properties of this tissue, and the pressurization of its interstitial fluid under loading. Direct measurements of this interstitial fluid pressure brough new insights and evidence with regard to cartilage lubrication, which became a major topic of investigation in the Musculoskeletal Biomechanics Laboratory.

Since 1996, Prof. Ateshian has established a close collaboration with Professor Clark T. Hung in the area of cartilage tissue engineering. This highly fruitful collaboration has led to important breakthroughs in this field, with notable advances in the understanding of the role of mechanical loading in engineered cartilage growth and development. This collaborative effort has also extended to the fields of solute transport in loaded tissues and tissue constructs, and cell mechanics, producing insights into the cell's mechano-electrochemical environment and its response to mechanical and osmotic loading.

Prof. Ateshian has also invested significant efforts in the modeling of biological tissues and cells using Mixture Theory. He has placed a particular effort in understanding the role of chemical reactions in mixtures, to address important challenges such as the modeling of tissue growth, and active transport processes.

Insights gained from these studies have led to other stimulating collaborations, with Professor Kevin D. Costa in the investigation of the role of proteoglycans in vascular wall mechanics, and with Professor David Elad in the area of oocyte mechanics.

To promote greater dissemination of these theoretical advances in the modeling of biological tissues, Prof. Ateshian has established a close collaboration with Professor Jeffrey A. Weiss of the University of Utah. In an effort involving several members of Columbia's Musculoskeletal Biomechanics Laboratory and Utah's Musculoskeletal Research Laboratories, these investigators are developing a free, open source, finite element program to model mechanics and transport in tissues and cells.

Curriculum Vitae (February 2016, PDF 640 KB)

Ateshian, G. A., Soslowsky, L. J., and Mow, V. C., 1991. Quantitation of articular surface topography and cartilage thickness in knee joints using stereophotogrammetry. J Biomech 24, 761-776, PubMed.

Ateshian, G. A., Rosenwasser, M. P., and Mow, V. C., 1992. Curvature characteristics and congruence of the thumb carpometacarpal joint: differences between female and male joints. J Biomech 25, 591-607, PubMed.

Soslowsky, L. J., Flatow, E. L., Bigliani, L. U., Pawluk, R. J., Ateshian, G. A., and Mow, V. C., 1992. Quantitation of in situ contact areas at the glenohumeral joint: a biomechanical study. J Orthop Res 10, 524-534, PubMed.

Ateshian, G. A., 1993. A B-spline least-squares surface-fitting method for articular surfaces of diarthrodial joints. J Biomech Eng 115, 366-373, PubMed.

Mow, V. C., Ateshian, G. A., and Spilker, R. L., 1993. Biomechanics of diarthrodial joints: a review of twenty years of progress. J Biomech Eng 115, 460-467, PubMed.

Ateshian, G. A., Kwak, S. D., Soslowsky, L. J., and Mow, V. C., 1994. A stereophotogrammetric method for determining in situ contact areas in diarthrodial joints, and a comparison with other methods. J Biomech 27, 111-124, PubMed.

Ateshian, G. A., Lai, W. M., Zhu, W. B., and Mow, V. C., 1994. An asymptotic solution for the contact of two biphasic cartilage layers. J Biomech 27, 1347-1360, PubMed.

Flatow, E. L., Ateshian, G. A., Soslowsky, L. J., Pawluk, R. J., Grelsamer, R. P., Mow, V. C., and Bigliani, L. U., 1994. Computer simulation of glenohumeral and patellofemoral subluxation. Estimating pathological articular contact. Clin Orthop Relat Res, 28-33, PubMed.

Ateshian, G. A., Ark, J. W., Rosenwasser, M. P., Pawluk, R. J., Soslowsky, L. J., and Mow, V. C., 1995. Contact areas in the thumb carpometacarpal joint. J Orthop Res 13, 450-458, PubMed.

Ateshian, G. A., and Wang, H., 1995. A theoretical solution for the frictionless rolling contact of cylindrical biphasic articular cartilage layers. J Biomech 28, 1341-1355, PubMed.

Ateshian, G. A., 1997. A theoretical formulation for boundary friction in articular cartilage. J Biomech Eng 119, 81-86, PubMed.

Ateshian, G. A., and Wang, H., 1997. Rolling resistance of articular cartilage due to interstitial fluid flow. Proc Inst Mech Eng H 211, 419-424, PubMed.

Ateshian, G. A., Warden, W. H., Kim, J. J., Grelsamer, R. P., and Mow, V. C., 1997. Finite deformation biphasic material properties of bovine articular cartilage from confined compression experiments. J Biomech 30, 1157-1164, PubMed.

Kwak, S. D., Colman, W. W., Ateshian, G. A., Grelsamer, R. P., Henry, J. H., and Mow, V. C., 1997. Anatomy of the human patellofemoral joint articular cartilage: surface curvature analysis. J Orthop Res 15, 468-472, PubMed.

Wang, H., and Ateshian, G. A., 1997. The normal stress effect and equilibrium friction coefficient of articular cartilage under steady frictional shear. J Biomech 30, 771-776, PubMed.

Ahmad, C. S., Kwak, S. D., Ateshian, G. A., Warden, W. H., Steadman, J. R., and Mow, V. C., 1998. Effects of patellar tendon adhesion to the anterior tibia on knee mechanics. Am J Sports Med 26, 715-724, PubMed.

Soltz, M. A., and Ateshian, G. A., 1998. Experimental verification and theoretical prediction of cartilage interstitial fluid pressurization at an impermeable contact interface in confined compression. J Biomech 31, 927-934, PubMed.

Xu, L., Strauch, R. J., Ateshian, G. A., Pawluk, R. J., Mow, V. C., and Rosenwasser, M. P., 1998. Topography of the osteoarthritic thumb carpometacarpal joint and its variations with regard to gender, age, site, and osteoarthritic stage. J Hand Surg Am 23, 454-464, PubMed.

Cohen, Z. A., McCarthy, D. M., Kwak, S. D., Legrand, P., Fogarasi, F., Ciaccio, E. J., and Ateshian, G. A., 1999. Knee cartilage topography, thickness, and contact areas from MRI: in-vitro calibration and in-vivo measurements. Osteoarthritis Cartilage 7, 95-109, PubMed.

Donzelli, P. S., Spilker, R. L., Ateshian, G. A., and Mow, V. C., 1999. Contact analysis of biphasic transversely isotropic cartilage layers and correlations with tissue failure. J Biomech 32, 1037-1047, PubMed.

Kwak, S. D., Ahmad, C. S., Gardner, T. R., Grelsamer, R. P., Henry, J. H., Blankevoort, L., Ateshian, G. A., and Mow, V. C., 2000. Hamstrings and iliotibial band forces affect knee kinematics and contact pattern. J Orthop Res 18, 101-108, PubMed.

Kwak, S. D., Blankevoort, L., and Ateshian, G. A., 2000. A Mathematical Formulation for 3D Quasi-Static Multibody Models of Diarthrodial Joints. Comput Methods Biomech Biomed Engin 3, 41-64, PubMed.

Lai, W. M., Mow, V. C., Sun, D. D., and Ateshian, G. A., 2000. On the electric potentials inside a charged soft hydrated biological tissue: streaming potential versus diffusion potential. J Biomech Eng 122, 336-346, PubMed.

Mauck, R. L., Soltz, M. A., Wang, C. C., Wong, D. D., Chao, P. H., Valhmu, W. B., Hung, C. T., and Ateshian, G. A., 2000. Functional tissue engineering of articular cartilage through dynamic loading of chondrocyte-seeded agarose gels. J Biomech Eng 122, 252-260, PubMed.

Rivers, P. A., Rosenwasser, M. P., Mow, V. C., Pawluk, R. J., Strauch, R. J., Sugalski, M. T., and Ateshian, G. A., 2000. Osteoarthritic changes in the biochemical composition of thumb carpometacarpal joint cartilage and correlation with biomechanical properties. J Hand Surg Am 25, 889-898, PubMed.

Soltz, M. A., and Ateshian, G. A., 2000. A Conewise Linear Elasticity mixture model for the analysis of tension-compression nonlinearity in articular cartilage. J Biomech Eng 122, 576-586, PMCID: PMC2854000, PubMed.

Soltz, M. A., and Ateshian, G. A., 2000. Interstitial fluid pressurization during confined compression cyclical loading of articular cartilage. Ann Biomed Eng 28, 150-159, PubMed.

Ahmad, C. S., Cohen, Z. A., Levine, W. N., Ateshian, G. A., and Mow, V. C., 2001. Biomechanical and topographic considerations for autologous osteochondral grafting in the knee. Am J Sports Med 29, 201-206, PubMed.

Cohen, Z. A., Roglic, H., Grelsamer, R. P., Henry, J. H., Levine, W. N., Mow, V. C., and Ateshian, G. A., 2001. Patellofemoral stresses during open and closed kinetic chain exercises. An analysis using computer simulation. Am J Sports Med 29, 480-487, PubMed.

Dykyj, D., Ateshian, G. A., Trepal, M. J., and MacDonald, L. R., 2001. Articular geometry of the medial tarsometatarsal joint in the foot: comparison of metatarsus primus adductus and metatarsus primus rectus. J Foot Ankle Surg 40, 357-365, PubMed.

Huang, C. Y., Mow, V. C., and Ateshian, G. A., 2001. The role of flow-independent viscoelasticity in the biphasic tensile and compressive responses of articular cartilage. J Biomech Eng 123, 410-417, PubMed.

Kelkar, R., Wang, V. M., Flatow, E. L., Newton, P. M., Ateshian, G. A., Bigliani, L. U., Pawluk, R. J., and Mow, V. C., 2001. Glenohumeral mechanics: a study of articular geometry, contact, and kinematics. J Shoulder Elbow Surg 10, 73-84, PubMed.

Kitano, T., Ateshian, G. A., Mow, V. C., Kadoya, Y., and Yamano, Y., 2001. Constituents and pH changes in protein rich hyaluronan solution affect the biotribological properties of artificial articular joints. J Biomech 34, 1031-1037, PubMed.

Lai, W. M., Sun, D. D., Ateshian, G. A., Guo, X. E., and Mow, V. C., 2002. Electrical signals for chondrocytes in cartilage. Biorheology 39, 39-45, PubMed.

Mauck, R. L., Seyhan, S. L., Ateshian, G. A., and Hung, C. T., 2002. Influence of seeding density and dynamic deformational loading on the developing structure/function relationships of chondrocyte-seeded agarose hydrogels. Ann Biomed Eng 30, 1046-1056, PubMed.

Wang, C. C., Deng, J. M., Ateshian, G. A., and Hung, C. T., 2002. An automated approach for direct measurement of two-dimensional strain distributions within articular cartilage under unconfined compression. J Biomech Eng 124, 557-567, PubMed.

Wang, C. C., Guo, X. E., Sun, D., Mow, V. C., Ateshian, G. A., and Hung, C. T., 2002. The functional environment of chondrocytes within cartilage subjected to compressive loading: a theoretical and experimental approach. Biorheology 39, 11-25, PubMed.

Ahmad, C. S., Cohen, Z. A., Levine, W. N., Gardner, T. R., Ateshian, G. A., and Mow, V. C., 2003. Codominance of the individual posterior cruciate ligament bundles. An analysis of bundle lengths and orientation. Am J Sports Med 31, 221-225, PubMed.

Brown, G. D., 3rd, Roh, M. S., Strauch, R. J., Rosenwasser, M. P., Ateshian, G. A., and Mow, V. C., 2003. Radiography and visual pathology of the osteoarthritic scaphotrapezio-trapezoidal joint, and its relationship to trapeziometacarpal osteoarthritis. J Hand Surg Am 28, 739-743, PubMed.

Cohen, Z. A., Henry, J. H., McCarthy, D. M., Mow, V. C., and Ateshian, G. A., 2003. Computer simulations of patellofemoral joint surgery. Patient-specific models for tuberosity transfer. Am J Sports Med 31, 87-98, PubMed.

Cohen, Z. A., Mow, V. C., Henry, J. H., Levine, W. N., and Ateshian, G. A., 2003. Templates of the cartilage layers of the patellofemoral joint and their use in the assessment of osteoarthritic cartilage damage. Osteoarthritis Cartilage 11, 569-579, PubMed.

Huang, C. Y., Soltz, M. A., Kopacz, M., Mow, V. C., and Ateshian, G. A., 2003. Experimental verification of the roles of intrinsic matrix viscoelasticity and tension-compression nonlinearity in the biphasic response of cartilage. J Biomech Eng 125, 84-93, PubMed.

Hung, C. T., Lima, E. G., Mauck, R. L., Takai, E., LeRoux, M. A., Lu, H. H., Stark, R. G., Guo, X. E., and Ateshian, G. A., 2003. Anatomically shaped osteochondral constructs for articular cartilage repair. J Biomech 36, 1853-1864, PubMed.

Koff, M. F., Ugwonali, O. F., Strauch, R. J., Rosenwasser, M. P., Ateshian, G. A., and Mow, V. C., 2003. Sequential wear patterns of the articular cartilage of the thumb carpometacarpal joint in osteoarthritis. J Hand Surg Am 28, 597-604, PubMed.

Krishnan, R., Park, S., Eckstein, F., and Ateshian, G. A., 2003. Inhomogeneous cartilage properties enhance superficial interstitial fluid support and frictional properties, but do not provide a homogeneous state of stress. J Biomech Eng 125, 569-577, PMCID: PMC2842189, PubMed.

Mauck, R. L., Hung, C. T., and Ateshian, G. A., 2003. Modeling of neutral solute transport in a dynamically loaded porous permeable gel: implications for articular cartilage biosynthesis and tissue engineering. J Biomech Eng 125, 602-614, PMCID: PMC2854001, PubMed.

Mauck, R. L., Nicoll, S. B., Seyhan, S. L., Ateshian, G. A., and Hung, C. T., 2003. Synergistic action of growth factors and dynamic loading for articular cartilage tissue engineering. Tissue Eng 9, 597-611, PubMed.

Mauck, R. L., Wang, C. C., Oswald, E. S., Ateshian, G. A., and Hung, C. T., 2003. The role of cell seeding density and nutrient supply for articular cartilage tissue engineering with deformational loading. Osteoarthritis Cartilage 11, 879-890, PubMed.

Morrison, B., 3rd, Cater, H. L., Wang, C. C., Thomas, F. C., Hung, C. T., Ateshian, G. A., and Sundstrom, L. E., 2003. A tissue level tolerance criterion for living brain developed with an in vitro model of traumatic mechanical loading. Stapp Car Crash J 47, 93-105, PubMed.

Park, S., Krishnan, R., Nicoll, S. B., and Ateshian, G. A., 2003. Cartilage interstitial fluid load support in unconfined compression. J Biomech 36, 1785-1796, PMCID: PMC2833094, PubMed.

Soltz, M. A., Basalo, I. M., and Ateshian, G. A., 2003. Hydrostatic pressurization and depletion of trapped lubricant pool during creep contact of a rippled indenter against a biphasic articular cartilage layer. J Biomech Eng 125, 585-593, PMCID: PMC2842086, PubMed.

Wang, C. C., Chahine, N. O., Hung, C. T., and Ateshian, G. A., 2003. Optical determination of anisotropic material properties of bovine articular cartilage in compression. J Biomech 36, 339-353, PMCID: PMC2809654, PubMed.

Ateshian, G. A., Chahine, N. O., Basalo, I. M., and Hung, C. T., 2004. The correspondence between equilibrium biphasic and triphasic material properties in mixture models of articular cartilage. J Biomech 37, 391-400, PMCID: PMC2819758, PubMed.

Basalo, I. M., Mauck, R. L., Kelly, T. A., Nicoll, S. B., Chen, F. H., Hung, C. T., and Ateshian, G. A., 2004. Cartilage interstitial fluid load support in unconfined compression following enzymatic digestion. J Biomech Eng 126, 779-786, PMCID: PMC3726345, PubMed.

Chahine, N. O., Wang, C. C., Hung, C. T., and Ateshian, G. A., 2004. Anisotropic strain-dependent material properties of bovine articular cartilage in the transitional range from tension to compression. J Biomech 37, 1251-1261, PMCID: PMC2819725, PubMed.

Hung, C. T., Mauck, R. L., Wang, C. C., Lima, E. G., and Ateshian, G. A., 2004. A paradigm for functional tissue engineering of articular cartilage via applied physiologic deformational loading. Ann Biomed Eng 32, 35-49, PubMed.

Kelly, T. A., Wang, C. C., Mauck, R. L., Ateshian, G. A., and Hung, C. T., 2004. Role of cell-associated matrix in the development of free-swelling and dynamically loaded chondrocyte-seeded agarose gels. Biorheology 41, 223-237, PubMed.

Krishnan, R., Caligaris, M., Mauck, R. L., Hung, C. T., Costa, K. D., and Ateshian, G. A., 2004. Removal of the superficial zone of bovine articular cartilage does not increase its frictional coefficient. Osteoarthritis Cartilage 12, 947-955, PMCID: PMC2828954, PubMed.

Krishnan, R., Kopacz, M., and Ateshian, G. A., 2004. Experimental verification of the role of interstitial fluid pressurization in cartilage lubrication. J Orthop Res 22, 565-570, PMCID: PMC2842190, PubMed.

Lima, E. G., Mauck, R. L., Han, S. H., Park, S., Ng, K. W., Ateshian, G. A., and Hung, C. T., 2004. Functional tissue engineering of chondral and osteochondral constructs. Biorheology 41, 577-590, PubMed.

Park, S., Costa, K. D., and Ateshian, G. A., 2004. Microscale frictional response of bovine articular cartilage from atomic force microscopy. J Biomech 37, 1679-1687, PMCID: PMC2809665, PubMed.

Park, S., Hung, C. T., and Ateshian, G. A., 2004. Mechanical response of bovine articular cartilage under dynamic unconfined compression loading at physiological stress levels. Osteoarthritis Cartilage 12, 65-73, PubMed.

Ateshian, G. A., and Hung, C. T., 2005. Patellofemoral joint biomechanics and tissue engineering. Clin Orthop Relat Res, 81-90, PMCID: PMC3786422, PubMed.

Basalo, I. M., Raj, D., Krishnan, R., Chen, F. H., Hung, C. T., and Ateshian, G. A., 2005. Effects of enzymatic degradation on the frictional response of articular cartilage in stress relaxation. J Biomech 38, 1343-1349, PMCID: PMC2833092, PubMed.

Chahine, N. O., Chen, F. H., Hung, C. T., and Ateshian, G. A., 2005. Direct measurement of osmotic pressure of glycosaminoglycan solutions by membrane osmometry at room temperature. Biophys J 89, 1543-1550, PMCID: PMC1366659, PubMed.

Huang, C. Y., Stankiewicz, A., Ateshian, G. A., and Mow, V. C., 2005. Anisotropy, inhomogeneity, and tension-compression nonlinearity of human glenohumeral cartilage in finite deformation. J Biomech 38, 799-809, PMCID: PMC3786419, PubMed.

Krishnan, R., Mariner, E. N., and Ateshian, G. A., 2005. Effect of dynamic loading on the frictional response of bovine articular cartilage. J Biomech 38, 1665-1673, PubMed.

Ng, K. W., Wang, C. C., Mauck, R. L., Kelly, T. A., Chahine, N. O., Costa, K. D., Ateshian, G. A., and Hung, C. T., 2005. A layered agarose approach to fabricate depth-dependent inhomogeneity in chondrocyte-seeded constructs. J Orthop Res 23, 134-141, PubMed.

Wang, V. M., Krishnan, R., Ugwonali, O. F., Flatow, E. L., Bigliani, L. U., and Ateshian, G. A., 2005. Biomechanical evaluation of a novel glenoid design in total shoulder arthroplasty. J Shoulder Elbow Surg 14, 129S-140S, PubMed.

Ateshian, G. A., Likhitpanichkul, M., and Hung, C. T., 2006. A mixture theory analysis for passive transport in osmotic loading of cells. J Biomech 39, 464-475, PMCID: PMC2859701, PubMed.

Basalo, I. M., Chen, F. H., Hung, C. T., and Ateshian, G. A., 2006. Frictional response of bovine articular cartilage under creep loading following proteoglycan digestion with chondroitinase ABC. J Biomech Eng 128, 131-134, PMCID: PMC2819726, PubMed.

Ho, M. M., Kelly, T. A., Guo, X. E., Ateshian, G. A., and Hung, C. T., 2006. Spatially varying material properties of the rat caudal intervertebral disc. Spine (Phila Pa 1976) 31, E486-493, PubMed.

Kelly, T. A., Ng, K. W., Wang, C. C., Ateshian, G. A., and Hung, C. T., 2006. Spatial and temporal development of chondrocyte-seeded agarose constructs in free-swelling and dynamically loaded cultures. J Biomech 39, 1489-1497, PubMed.

Lima, E. G., Bian, L., Mauck, R. L., Byers, B. A., Tuan, R. S., Ateshian, G. A., and Hung, C. T., 2006. The effect of applied compressive loading on tissue-engineered cartilage constructs cultured with TGF-beta3. Conf Proc IEEE Eng Med Biol Soc 1, 779-782, PubMed.

Moffat, K. L., Sun, W. H., Chahine, N. O., Pena, P. E., Doty, S. B., Hung, C. T., Ateshian, G. A., and Lu, H. H., 2006. Characterization of the mechanical properties and mineral distribution of the anterior cruciate ligament-to-bone insertion site. Conf Proc IEEE Eng Med Biol Soc 1, 2366-2369, PubMed.

Ng, K. W., Mauck, R. L., Statman, L. Y., Lin, E. Y., Ateshian, G. A., and Hung, C. T., 2006. Dynamic deformational loading results in selective application of mechanical stimulation in a layered, tissue-engineered cartilage construct. Biorheology 43, 497-507, PubMed.

Oswald, E. S., Chao, P. H., Bulinski, J. C., Ateshian, G. A., and Hung, C. T., 2006. Chondrocyte nuclear response to osmotic loading. Conf Proc IEEE Eng Med Biol Soc 1, 3659-3661, PubMed.

Park, S., and Ateshian, G. A., 2006. Dynamic response of immature bovine articular cartilage in tension and compression, and nonlinear viscoelastic modeling of the tensile response. J Biomech Eng 128, 623-630, PMCID: PMC2842191, PubMed.

Albro, M. B., Chahine, N. O., Caligaris, M., Wei, V. I., Likhitpanichkul, M., Ng, K. W., Hung, C. T., and Ateshian, G. A., 2007. Osmotic loading of spherical gels: a biomimetic study of hindered transport in the cell protoplasm. J Biomech Eng 129, 503-510, PMCID: PMC2828939, PubMed.

Ateshian, G. A., 2007. Anisotropy of fibrous tissues in relation to the distribution of tensed and buckled fibers. J Biomech Eng 129, 240-249, PMCID: PMC2805028, PubMed.

Ateshian, G. A., 2007. Artificial cartilage: weaving in three dimensions. Nat Mater 6, 89-90, PubMed.

Ateshian, G. A., 2007. On the theory of reactive mixtures for modeling biological growth. Biomech Model Mechanobiol 6, 423-445, PMCID: PMC3834581, PubMed.

Ateshian, G. A., 2007. Special issue on cartilage (part II). Biomech Model Mechanobiol 6, 1-3, PubMed.

Ateshian, G. A., Costa, K. D., and Hung, C. T., 2007. A theoretical analysis of water transport through chondrocytes. Biomech Model Mechanobiol 6, 91-101, PMCID: PMC2853978, PubMed.

Ateshian, G. A., Ellis, B. J., and Weiss, J. A., 2007. Equivalence between short-time biphasic and incompressible elastic material responses. J Biomech Eng 129, 405-412, PMCID: PMC3312381, PubMed.

Basalo, I. M., Chahine, N. O., Kaplun, M., Chen, F. H., Hung, C. T., and Ateshian, G. A., 2007. Chondroitin sulfate reduces the friction coefficient of articular cartilage. J Biomech 40, 1847-1854, PubMed.

Carter, M. J., Basalo, I. M., and Ateshian, G. A., 2007. The temporal response of the friction coefficient of articular cartilage depends on the contact area. J Biomech 40, 3257-3260, PMCID: PMC2094001, PubMed.

Chahine, N. O., Ateshian, G. A., and Hung, C. T., 2007. The effect of finite compressive strain on chondrocyte viability in statically loaded bovine articular cartilage. Biomech Model Mechanobiol 6, 103-111, PubMed.

Chahine, N. O., Hung, C. T., and Ateshian, G. A., 2007. In-situ measurements of chondrocyte deformation under transient loading. Eur Cell Mater 13, 100-111; discussion 111, PubMed.

Lima, E. G., Bian, L., Ng, K. W., Mauck, R. L., Byers, B. A., Tuan, R. S., Ateshian, G. A., and Hung, C. T., 2007. The beneficial effect of delayed compressive loading on tissue-engineered cartilage constructs cultured with TGF-beta3. Osteoarthritis Cartilage 15, 1025-1033, PMCID: PMC2724596, PubMed.

Ng, K. W., Saliman, J. D., Lin, E. Y., Statman, L. Y., Kugler, L. E., Lo, S. B., Ateshian, G. A., and Hung, C. T., 2007. Culture duration modulates collagen hydrolysate-induced tissue remodeling in chondrocyte-seeded agarose hydrogels. Ann Biomed Eng 35, 1914-1923, PubMed.

Pillai, R. R., Thoomukuntla, B., Ateshian, G. A., and Fischer, K. J., 2007. MRI-based modeling for evaluation of in vivo contact mechanics in the human wrist during active light grasp. J Biomech 40, 2781-2787, PubMed.

Albro, M. B., Chahine, N. O., Li, R., Yeager, K., Hung, C. T., and Ateshian, G. A., 2008. Dynamic loading of deformable porous media can induce active solute transport. J Biomech 41, 3152-3157, PMCID: PMC2633098, PubMed.

Azeloglu, E. U., Albro, M. B., Thimmappa, V. A., Ateshian, G. A., and Costa, K. D., 2008. Heterogeneous transmural proteoglycan distribution provides a mechanism for regulating residual stresses in the aorta. Am J Physiol Heart Circ Physiol 294, H1197-1205, PubMed.

Bian, L., Lima, E. G., Angione, S. L., Ng, K. W., Williams, D. Y., Xu, D., Stoker, A. M., Cook, J. L., Ateshian, G. A., and Hung, C. T., 2008. Mechanical and biochemical characterization of cartilage explants in serum-free culture. J Biomech 41, 1153-1159, PMCID: PMC3387278, PubMed.

Caligaris, M., and Ateshian, G. A., 2008. Effects of sustained interstitial fluid pressurization under migrating contact area, and boundary lubrication by synovial fluid, on cartilage friction. Osteoarthritis Cartilage 16, 1220-1227, PMCID: PMC2622427, PubMed.

Canal, C. E., Hung, C. T., and Ateshian, G. A., 2008. Two-dimensional strain fields on the cross-section of the bovine humeral head under contact loading. J Biomech 41, 3145-3151, PMCID: PMC2633100, PubMed.

Kelly, T. A., Fisher, M. B., Oswald, E. S., Tai, T., Mauck, R. L., Ateshian, G. A., and Hung, C. T., 2008. Low-serum media and dynamic deformational loading in tissue engineering of articular cartilage. Ann Biomed Eng 36, 769-779, PubMed.

Lima, E. G., Grace Chao, P. H., Ateshian, G. A., Bal, B. S., Cook, J. L., Vunjak-Novakovic, G., and Hung, C. T., 2008. The effect of devitalized trabecular bone on the formation of osteochondral tissue-engineered constructs. Biomaterials 29, 4292-4299, PMCID: PMC2562244, PubMed.

Lima, E. G., Tan, A. R., Tai, T., Bian, L., Ateshian, G. A., Cook, J. L., and Hung, C. T., 2008. Physiologic deformational loading does not counteract the catabolic effects of interleukin-1 in long-term culture of chondrocyte-seeded agarose constructs. J Biomech 41, 3253-3259, PMCID: PMC2724593, PubMed.

Lima, E. G., Tan, A. R., Tai, T., Bian, L., Stoker, A. M., Ateshian, G. A., Cook, J. L., and Hung, C. T., 2008. Differences in interleukin-1 response between engineered and native cartilage. Tissue Eng Part A 14, 1721-1730, PubMed.

Moffat, K. L., Sun, W. H., Pena, P. E., Chahine, N. O., Doty, S. B., Ateshian, G. A., Hung, C. T., and Lu, H. H., 2008. Characterization of the structure-function relationship at the ligament-to-bone interface. Proc Natl Acad Sci U S A 105, 7947-7952, PMCID: PMC2430342, PubMed.

Ng, K. W., DeFrancis, J. G., Kugler, L. E., Kelly, T. A., Ho, M. M., O'Conor, C. J., Ateshian, G. A., and Hung, C. T., 2008. Amino acids supply in culture media is not a limiting factor in the matrix synthesis of engineered cartilage tissue. Amino Acids 35, 433-438, PMCID: PMC3769193, PubMed.

Oswald, E. S., Chao, P. H., Bulinski, J. C., Ateshian, G. A., and Hung, C. T., 2008. Dependence of zonal chondrocyte water transport properties on osmotic environment. Cell Mol Bioeng 1, 339-348, PMCID: PMC2792913, PubMed.

Park, S., Nicoll, S. B., Mauck, R. L., and Ateshian, G. A., 2008. Cartilage mechanical response under dynamic compression at physiological stress levels following collagenase digestion. Ann Biomed Eng 36, 425-434, PubMed.

Albro, M. B., Petersen, L. E., Li, R., Hung, C. T., and Ateshian, G. A., 2009. Influence of the partitioning of osmolytes by the cytoplasm on the passive response of cells to osmotic loading. Biophys J 97, 2886-2893, PMCID: PMC2784563, PubMed.

Albro, M. B., Rajan, V., Li, R., Hung, C. T., and Ateshian, G. A., 2009. Characterization of the Concentration-Dependence of Solute Diffusivity and Partitioning in a Model Dextran-Agarose Transport System. Cell Mol Bioeng 2, 295-305, PMCID: PMC2996616, PubMed.

Ateshian, G. A., 2009. The role of interstitial fluid pressurization in articular cartilage lubrication. J Biomech 42, 1163-1176, PMCID: PMC2758165, PubMed.

Ateshian, G. A., and Costa, K. D., 2009. A frame-invariant formulation of Fung elasticity. J Biomech 42, 781-785, PMCID: PMC3612496, PubMed.

Ateshian, G. A., Costa, K. D., Azeloglu, E. U., Morrison, B., 3rd, and Hung, C. T., 2009. Continuum modeling of biological tissue growth by cell division, and alteration of intracellular osmolytes and extracellular fixed charge density. J Biomech Eng 131, 101001, PMCID: PMC2860886, PubMed.

Ateshian, G. A., and Friedman, M. H., 2009. Integrative biomechanics: a paradigm for clinical applications of fundamental mechanics. J Biomech 42, 1444-1451, PubMed.

Ateshian, G. A., Rajan, V., Chahine, N. O., Canal, C. E., and Hung, C. T., 2009. Modeling the matrix of articular cartilage using a continuous fiber angular distribution predicts many observed phenomena. J Biomech Eng 131, 061003, PMCID: PMC2842192, PubMed.

Bian, L., Angione, S. L., Ng, K. W., Lima, E. G., Williams, D. Y., Mao, D. Q., Ateshian, G. A., and Hung, C. T., 2009. Influence of decreasing nutrient path length on the development of engineered cartilage. Osteoarthritis Cartilage 17, 677-685, PMCID: PMC3387279, PubMed.

Bian, L., Crivello, K. M., Ng, K. W., Xu, D., Williams, D. Y., Ateshian, G. A., and Hung, C. T., 2009. Influence of temporary chondroitinase ABC-induced glycosaminoglycan suppression on maturation of tissue-engineered cartilage. Tissue Eng Part A 15, 2065-2072, PMCID: PMC2792113, PubMed.

Bian, L., Kaplun, M., Williams, D. Y., Xu, D., Ateshian, G. A., and Hung, C. T., 2009. Influence of chondroitin sulfate on the biochemical, mechanical and frictional properties of cartilage explants in long-term culture. J Biomech 42, 286-290, PMCID: PMC2819724, PubMed.

Caligaris, M., Canal, C. E., Ahmad, C. S., Gardner, T. R., and Ateshian, G. A., 2009. Investigation of the frictional response of osteoarthritic human tibiofemoral joints and the potential beneficial tribological effect of healthy synovial fluid. Osteoarthritis Cartilage 17, 1327-1332, PMCID: PMC2753744, PubMed.

Chahine, N. O., Albro, M. B., Lima, E. G., Wei, V. I., Dubois, C. R., Hung, C. T., and Ateshian, G. A., 2009. Effect of dynamic loading on the transport of solutes into agarose hydrogels. Biophys J 97, 968-975, PMCID: PMC2726307, PubMed.

Guterl, C. C., Gardner, T. R., Rajan, V., Ahmad, C. S., Hung, C. T., and Ateshian, G. A., 2009. Two-dimensional strain fields on the cross-section of the human patellofemoral joint under physiological loading. J Biomech 42, 1275-1281, PMCID: PMC2980285, PubMed.

Kelly, T. A., Ng, K. W., Ateshian, G. A., and Hung, C. T., 2009. Analysis of radial variations in material properties and matrix composition of chondrocyte-seeded agarose hydrogel constructs. Osteoarthritis Cartilage 17, 73-82, PMCID: PMC2821566, PubMed.

Lima, E. G., Tan, A. R., Tai, T., Marra, K. G., DeFail, A., Ateshian, G. A., and Hung, C. T., 2009. Genipin enhances the mechanical properties of tissue-engineered cartilage and protects against inflammatory degradation when used as a medium supplement. J Biomed Mater Res A 91, 692-700, PMCID: PMC2767416, PubMed.

Ng, K. W., Ateshian, G. A., and Hung, C. T., 2009. Zonal chondrocytes seeded in a layered agarose hydrogel create engineered cartilage with depth-dependent cellular and mechanical inhomogeneity. Tissue Eng Part A 15, 2315-2324, PMCID: PMC2787199, PubMed.

Ng, K. W., Kugler, L. E., Doty, S. B., Ateshian, G. A., and Hung, C. T., 2009. Scaffold degradation elevates the collagen content and dynamic compressive modulus in engineered articular cartilage. Osteoarthritis Cartilage 17, 220-227, PMCID: PMC2795572, PubMed.

Ng, K. W., Mauck, R. L., Wang, C. C., Kelly, T. A., Ho, M. M., Chen, F. H., Ateshian, G. A., and Hung, C. T., 2009. Duty Cycle of Deformational Loading Influences the Growth of Engineered Articular Cartilage. Cell Mol Bioeng 2, 386-394, PMCID: PMC2918904, PubMed.

Park, S., Costa, K. D., Ateshian, G. A., and Hong, K. S., 2009. Mechanical properties of bovine articular cartilage under microscale indentation loading from atomic force microscopy. Proc Inst Mech Eng H 223, 339-347, PubMed.

Albro, M. B., Li, R., Banerjee, R. E., Hung, C. T., and Ateshian, G. A., 2010. Validation of theoretical framework explaining active solute uptake in dynamically loaded porous media. J Biomech 43, 2267-2273, PMCID: PMC2993250, PubMed.

Ateshian, G. A., Maas, S., and Weiss, J. A., 2010. Finite element algorithm for frictionless contact of porous permeable media under finite deformation and sliding. J Biomech Eng 132, 061006, PMCID: PMC2953263, PubMed.

Ateshian, G. A., Morrison, B., 3rd, and Hung, C. T., 2010. Modeling of active transmembrane transport in a mixture theory framework. Ann Biomed Eng 38, 1801-1814, PMCID: PMC2913781, PubMed.

Ateshian, G. A., and Ricken, T., 2010. Multigenerational interstitial growth of biological tissues. Biomech Model Mechanobiol 9, 689-702, PMCID: PMC2970697, PubMed.

Ateshian, G. A., and Weiss, J. A., 2010. Anisotropic hydraulic permeability under finite deformation. J Biomech Eng 132, 111004, PMCID: PMC3124784, PubMed.

Bian, L., Fong, J. V., Lima, E. G., Stoker, A. M., Ateshian, G. A., Cook, J. L., and Hung, C. T., 2010. Dynamic mechanical loading enhances functional properties of tissue-engineered cartilage using mature canine chondrocytes. Tissue Eng Part A 16, 1781-1790, PMCID: PMC2952125, PubMed.

Bian, L., Stoker, A. M., Marberry, K. M., Ateshian, G. A., Cook, J. L., and Hung, C. T., 2010. Effects of dexamethasone on the functional properties of cartilage explants during long-term culture. Am J Sports Med 38, 78-85, PMCID: PMC2929560, PubMed.

Canal Guterl, C., Hung, C. T., and Ateshian, G. A., 2010. Electrostatic and non-electrostatic contributions of proteoglycans to the compressive equilibrium modulus of bovine articular cartilage. J Biomech 43, 1343-1350, PMCID: PMC2900255, PubMed.

Henninger, H. B., Underwood, C. J., Ateshian, G. A., and Weiss, J. A., 2010. Effect of sulfated glycosaminoglycan digestion on the transverse permeability of medial collateral ligament. J Biomech 43, 2567-2573, PMCID: PMC3152955, PubMed.

Jiang, J., Tang, A., Ateshian, G. A., Guo, X. E., Hung, C. T., and Lu, H. H., 2010. Bioactive stratified polymer ceramic-hydrogel scaffold for integrative osteochondral repair. Ann Biomed Eng 38, 2183-2196, PubMed.

Ng, K. W., Lima, E. G., Bian, L., O'Conor, C. J., Jayabalan, P. S., Stoker, A. M., Kuroki, K., Cook, C. R., Ateshian, G. A., Cook, J. L., and Hung, C. T., 2010. Passaged adult chondrocytes can form engineered cartilage with functional mechanical properties: a canine model. Tissue Eng Part A 16, 1041-1051, PMCID: PMC2862612, PubMed.

Tan, A. R., Dong, E. Y., Ateshian, G. A., and Hung, C. T., 2010. Response of engineered cartilage to mechanical insult depends on construct maturity. Osteoarthritis Cartilage 18, 1577-1585, PMCID: PMC3099249, PubMed.

Albro, M. B., Banerjee, R. E., Li, R., Oungoulian, S. R., Chen, B., del Palomar, A. P., Hung, C. T., and Ateshian, G. A., 2011. Dynamic loading of immature epiphyseal cartilage pumps nutrients out of vascular canals. J Biomech 44, 1654-1659, PMCID: PMC3124764, PubMed.

Ambrosi, D., Ateshian, G. A., Arruda, E. M., Cowin, S. C., Dumais, J., Goriely, A., Holzapfel, G. A., Humphrey, J. D., Kemkemer, R., Kuhl, E., Olberding, J. E., Taber, L. A., and Garikipati, K., 2011. Perspectives on biological growth and remodeling. J Mech Phys Solids 59, 863-883, PMCID: PMC3083065, PubMed.

Ateshian, G. A., 2011. The role of mass balance equations in growth mechanics illustrated in surface and volume dissolutions. J Biomech Eng 133, 011010, PMCID: PMC3086819, PubMed.

Ateshian, G. A., Albro, M. B., Maas, S., and Weiss, J. A., 2011. Finite element implementation of mechanochemical phenomena in neutral deformable porous media under finite deformation. J Biomech Eng 133, 081005, PMCID: PMC3431289, PubMed.

Ng, K. W., O'Conor, C. J., Kugler, L. E., Cook, J. L., Ateshian, G. A., and Hung, C. T., 2011. Transient supplementation of anabolic growth factors rapidly stimulates matrix synthesis in engineered cartilage. Ann Biomed Eng 39, 2491-2500, PMCID: PMC3387273, PubMed.

Oswald, E. S., Ahmed, H. S., Kramer, S. P., Bulinski, J. C., Ateshian, G. A., and Hung, C. T., 2011. Effects of hypertonic (NaCl) two-dimensional and three-dimensional culture conditions on the properties of cartilage tissue engineered from an expanded mature bovine chondrocyte source. Tissue Eng Part C Methods 17, 1041-1049, PMCID: PMC3205796, PubMed.

Sampat, S. R., O'Connell, G. D., Fong, J. V., Alegre-Aguaron, E., Ateshian, G. A., and Hung, C. T., 2011. Growth factor priming of synovium-derived stem cells for cartilage tissue engineering. Tissue Eng Part A 17, 2259-2265, PMCID: PMC3161099, PubMed.

Tan, A. R., Dong, E. Y., Andry, J. P., Bulinski, J. C., Ateshian, G. A., and Hung, C. T., 2011. Coculture of engineered cartilage with primary chondrocytes induces expedited growth. Clin Orthop Relat Res 469, 2735-2743, PMCID: PMC3171525, PubMed.

Albro, M. B., Cigan, A. D., Nims, R. J., Yeroushalmi, K. J., Oungoulian, S. R., Hung, C. T., and Ateshian, G. A., 2012. Shearing of synovial fluid activates latent TGF-beta. Osteoarthritis Cartilage 20, 1374-1382, PMCID: PMC3448789, PubMed.

Ateshian, G. A., and Humphrey, J. D., 2012. Continuum mixture models of biological growth and remodeling: past successes and future opportunities. Annu Rev Biomed Eng 14, 97-111, PubMed.

Ateshian, G. A., Maas, S., and Weiss, J. A., 2012. Solute transport across a contact interface in deformable porous media. J Biomech 45, 1023-1027, PMCID: PMC3351088, PubMed.

Ateshian, G. A., Morrison, B., 3rd, Holmes, J. W., and Hung, C. T., 2012. Mechanics of Cell Growth. Mech Res Commun 42, 118-125, PMCID: PMC3418607, PubMed.

Huang, A. H., Baker, B. M., Ateshian, G. A., and Mauck, R. L., 2012. Sliding contact loading enhances the tensile properties of mesenchymal stem cell-seeded hydrogels. Eur Cell Mater 24, 29-45, PubMed.

Lima, E. G., Durney, K. M., Sirsi, S. R., Nover, A. B., Ateshian, G. A., Borden, M. A., and Hung, C. T., 2012. Microbubbles as biocompatible porogens for hydrogel scaffolds. Acta Biomater 8, 4334-4341, PMCID: PMC3654399, PubMed.

Maas, S. A., Ellis, B. J., Ateshian, G. A., and Weiss, J. A., 2012. FEBio: finite elements for biomechanics. J Biomech Eng 134, 011005, PMCID: PMC3705975, PubMed.

O'Connell, G. D., Fong, J. V., Dunleavy, N., Joffe, A., Ateshian, G. A., and Hung, C. T., 2012. Trimethylamine N-oxide as a media supplement for cartilage tissue engineering. J Orthop Res 30, 1898-1905, PMCID: PMC3625430, PubMed.

O'Connell, G. D., Lima, E. G., Bian, L., Chahine, N. O., Albro, M. B., Cook, J. L., Ateshian, G. A., and Hung, C. T., 2012. Toward engineering a biological joint replacement. J Knee Surg 25, 187-196, PMCID: PMC3700804, PubMed.

Albro, M. B., Nims, R. J., Cigan, A. D., Yeroushalmi, K. J., Alliston, T., Hung, C. T., and Ateshian, G. A., 2013. Accumulation of exogenous activated TGF-beta in the superficial zone of articular cartilage. Biophys J 104, 1794-1804, PMCID: PMC3627867, PubMed.

Albro, M. B., Nims, R. J., Cigan, A. D., Yeroushalmi, K. J., Shim, J. J., Hung, C. T., and Ateshian, G. A., 2013. Dynamic mechanical compression of devitalized articular cartilage does not activate latent TGF-beta. J Biomech 46, 1433-1439, PMCID: PMC3810401, PubMed.

Ateshian, G. A., Maas, S., and Weiss, J. A., 2013. Multiphasic finite element framework for modeling hydrated mixtures with multiple neutral and charged solutes. J Biomech Eng 135, 111001, PMCID: PMC3792408, PubMed.

Cigan, A. D., Nims, R. J., Albro, M. B., Esau, J. D., Dreyer, M. P., Vunjak-Novakovic, G., Hung, C. T., and Ateshian, G. A., 2013. Insulin, ascorbate, and glucose have a much greater influence than transferrin and selenous acid on the in vitro growth of engineered cartilage in chondrogenic media. Tissue Eng Part A 19, 1941-1948, PMCID: PMC3725793, PubMed.

Henak, C. R., Ateshian, G. A., and Weiss, J. A., 2013. Finite Element Prediction of Transchondral Stress and Strain in the Human Hip. J Biomech Eng, PubMed.

Kelly, T. A., Roach, B. L., Weidner, Z. D., Mackenzie-Smith, C. R., O'Connell, G. D., Lima, E. G., Stoker, A. M., Cook, J. L., Ateshian, G. A., and Hung, C. T., 2013. Tissue-engineered articular cartilage exhibits tension-compression nonlinearity reminiscent of the native cartilage. J Biomech 46, 1784-1791, PMCID: PMC3713158, PubMed.

Nims, R. J., Cigan, A. D., Albro, M. B., Hung, C. T., and Ateshian, G. A., 2013. Synthesis rates and binding kinetics of matrix products in engineered cartilage constructs using chondrocyte-seeded agarose gels. J Biomech, PubMed.

Oungoulian, S. R., Chang, S., Bortz, O., Hehir, K. E., Zhu, K., Willis, C. E., Hung, C. T., and Ateshian, G. A., 2013. Articular cartilage wear characterization with a particle sizing and counting analyzer. J Biomech Eng 135, 024501, PMCID: PMC3660847, PubMed.

Sampat, S. R., Dermksian, M. V., Oungoulian, S. R., Winchester, R. J., Bulinski, J. C., Ateshian, G. A., and Hung, C. T., 2013. Applied osmotic loading for promoting development of engineered cartilage. J Biomech 46, 2674-2681, PubMed.

Alegre-Aguaron, E., Sampat, S. R., Xiong, J. C., Colligan, R. M., Bulinski, J. C., Cook, J. L., Ateshian, G. A., Brown, L. M., and Hung, C. T., 2014. Growth factor priming differentially modulates components of the extracellular matrix proteome in chondrocytes and synovium-derived stem cells. PLoS One 9, e88053, PMCID: PMC3917883, PubMed.

Ateshian, G. A., Nims, R. J., Maas, S., and Weiss, J. A., 2014. Computational modeling of chemical reactions and interstitial growth and remodeling involving charged solutes and solid-bound molecules. Biomech Model Mechanobiol 13, 1105-1120, PMCID: PMC4141041, PubMed.

Bhumiratana, S., Eton, R. E., Oungoulian, S. R., Wan, L. Q., Ateshian, G. A., and Vunjak-Novakovic, G., 2014. Large, stratified, and mechanically functional human cartilage grown in vitro by mesenchymal condensation. Proc Natl Acad Sci U S A 111, 6940-6945, PMCID: PMC4024923, PubMed.

Cigan, A. D., Nims, R. J., Albro, M. B., Vunjak-Novakovic, G., Hung, C. T., and Ateshian, G. A., 2014. Nutrient channels and stirring enhanced the composition and stiffness of large cartilage constructs. J Biomech 47, 3847-3854, PMCID: PMC4261053, PubMed.

Henak, C. R., Ateshian, G. A., and Weiss, J. A., 2014. Finite element prediction of transchondral stress and strain in the human hip. J Biomech Eng 136, 021021, PubMed.

Myers, K., and Ateshian, G. A., 2014. Interstitial growth and remodeling of biological tissues: tissue composition as state variables. J Mech Behav Biomed Mater 29, 544-556, PMCID: PMC3812404, PubMed.

Nims, R. J., Cigan, A. D., Albro, M. B., Hung, C. T., and Ateshian, G. A., 2014. Synthesis rates and binding kinetics of matrix products in engineered cartilage constructs using chondrocyte-seeded agarose gels. J Biomech 47, 2165-2172, PMCID: PMC4017010, PubMed.

O'Connell, G. D., Nims, R. J., Green, J., Cigan, A. D., Ateshian, G. A., and Hung, C. T., 2014. Time and dose-dependent effects of chondroitinase ABC on growth of engineered cartilage. Eur Cell Mater 27, 312-320, PMCID: PMC4096549, PubMed.

Oungoulian, S. R., Hehir, K. E., Zhu, K., Willis, C. E., Marinescu, A. G., Merali, N., Ahmad, C. S., Hung, C. T., and Ateshian, G. A., 2014. Effect of glutaraldehyde fixation on the frictional response of immature bovine articular cartilage explants. J Biomech 47, 694-701, PMCID: PMC3913559, PubMed.

Roccabianca, S., Ateshian, G. A., and Humphrey, J. D., 2014. Biomechanical roles of medial pooling of glycosaminoglycans in thoracic aortic dissection. Biomech Model Mechanobiol 13, 13-25, PMCID: PMC3918738, PubMed.

Ateshian, G. A., 2015. Viscoelasticity using reactive constrained solid mixtures. J Biomech 48, 941-947, PMCID: PMC4422403, PubMed.

Ateshian, G. A., Henak, C. R., and Weiss, J. A., 2015. Toward patient-specific articular contact mechanics. J Biomech 48, 779-786, PMCID: PMC4416416, PubMed.

Jones, B. K., Durney, K. M., Hung, C. T., and Ateshian, G. A., 2015. The friction coefficient of shoulder joints remains remarkably low over 24h of loading. J Biomech 48, 3945-3949, PMCID: PMC4707938, PubMed.

Nims, R. J., Cigan, A. D., Albro, M. B., Vunjak-Novakovic, G., Hung, C. T., and Ateshian, G. A., 2015. Matrix Production in Large Engineered Cartilage Constructs Is Enhanced by Nutrient Channels and Excess Media Supply. Tissue Eng Part C Methods 21, 747-757, PMCID: PMC4499772, PubMed.

Nover, A. B., Lee, S. L., Georgescu, M. S., Howard, D. R., Saunders, R. A., Yu, W. T., Klein, R. W., Napolitano, A. P., Ateshian, G. A., and Hung, C. T., 2015. Porous titanium bases for osteochondral tissue engineering. Acta Biomater 27, 286-293, PMCID: PMC4698168, PubMed.

O'Connell, G. D., Tan, A. R., Cui, V., Bulinski, J. C., Cook, J. L., Attur, M., Abramson, S. B., Ateshian, G. A., and Hung, C. T., 2015. Human chondrocyte migration behaviour to guide the development of engineered cartilage. J Tissue Eng Regen Med, PMCID: PMC4531108, PubMed.

Oungoulian, S. R., Durney, K. M., Jones, B. K., Ahmad, C. S., Hung, C. T., and Ateshian, G. A., 2015. Wear and damage of articular cartilage with friction against orthopedic implant materials. J Biomech 48, 1957-1964, PMCID: PMC4492870, PubMed.

Roach, B. L., Hung, C. T., Cook, J. L., Ateshian, G. A., and Tan, A. R., 2015. Fabrication of tissue engineered osteochondral grafts for restoring the articular surface of diarthrodial joints. Methods 84, 103-108, PMCID: PMC4667358, PubMed.

Tan, A. R., Alegre-Aguaron, E., O'Connell, G. D., VandenBerg, C. D., Aaron, R. K., Vunjak-Novakovic, G., Chloe Bulinski, J., Ateshian, G. A., and Hung, C. T., 2015. Passage-dependent relationship between mesenchymal stem cell mobilization and chondrogenic potential. Osteoarthritis Cartilage 23, 319-327, PMCID: PMC4369922, PubMed.

Tan, A. R., VandenBerg, C. D., Attur, M., Abramson, S. B., Knight, M. M., Bulinski, J. C., Ateshian, G. A., Cook, J. L., and Hung, C. T., 2015. Cytokine preconditioning of engineered cartilage provides protection against interleukin-1 insult. Arthritis Res Ther 17, 361, PMCID: PMC4704536, PubMed.

Albro, M. B., Nims, R. J., Durney, K. M., Cigan, A. D., Shim, J. J., Vunjak-Novakovic, G., Hung, C. T., and Ateshian, G. A., 2016. Heterogeneous engineered cartilage growth results from gradients of media-supplemented active TGF-beta and is ameliorated by the alternative supplementation of latent TGF-beta. Biomaterials 77, 173-185, PMCID: PMCIn Process, PubMed.

Hou, C., and Ateshian, G. A., 2016. A Gauss-Kronrod-Trapezoidal integration scheme for modeling biological tissues with continuous fiber distributions. Comput Methods Biomech Biomed Engin 19, 883-893, PubMed.

Hung, C. T., and Ateshian, G. A., 2016. Grading of osteoarthritic cartilage: Correlations between histology and biomechanics. J Orthop Res 34, 8-9, PubMed.

Jones, B., Hung, C. T., and Ateshian, G., 2016. Biphasic Analysis of Cartilage Stresses in the Patellofemoral Joint. J Knee Surg 29, 92-98, PMCID: PMC4747677, PubMed.

Nims, R. J., Durney, K. M., Cigan, A. D., Dusseaux, A., Hung, C. T., and Ateshian, G. A., 2016. Continuum theory of fibrous tissue damage mechanics using bond kinetics: application to cartilage tissue engineering. Interface Focus 6, 20150063, PMCID: PMC4686240, PubMed.

Nover, A. B., Hou, G. Y., Han, Y., Wang, S., O'Connell, G. D., Ateshian, G. A., Konofagou, E. E., and Hung, C. T., 2016. High intensity focused ultrasound as a tool for tissue engineering: Application to cartilage. Med Eng Phys 38, 192-198, PubMed.

Nover, A. B., Jones, B. K., Yu, W. T., Donovan, D. S., Podolnick, J. D., Cook, J. L., Ateshian, G. A., and Hung, C. T., 2016. A puzzle assembly strategy for fabrication of large engineered cartilage tissue constructs. J Biomech, PubMed.

Nover, A. B., Stefani, R. M., Lee, S. L., Ateshian, G. A., Stoker, A. M., Cook, J. L., and Hung, C. T., 2016. Long-term storage and preservation of tissue engineered articular cartilage. J Orthop Res 34, 141-148, PMCID: PMC4710567, PubMed.

500 W. 120th St., 134A Mudd, New York, NY 10027    212-854-4259                
©2014 Columbia University