Krista Durney

Ph.D. Candidate
Mudd 134A
(212) 854-4259

Education

  • B.E. Cooper Union, Engineering, May 2009
  • M.E. Cooper Union, Mechanical Engineering, Jan 2011

Krista began working in the Musculoskeletal Biomechanics Laboratory in the Fall of 2012 as a graduate student in Biomedical Engineering. Prior to joining the lab, she completed her master's thesis as a collaborative work between Cooper Union and Dr. Clark Hung's Cellular Engineering Laboratory at Columbia. This project aimed to improve tissue engineered cartilage growth by increasing solute availability to encapsulated cells. This has translated into new work exploring growth factor transport in engineered cartilage tissue. Krista currently studies cartilage mechanics, tribology, and cartilage damage toward a better understanding of osteoarthritis onset and prevention.

In her spare time, Krista enjoys dynamically loading her own cartilage in yoga and riding her bicycle around Manhattan. She also enjoys sci-fi books and films as she ponders the future of regenerative medicine.

Full-Length Papers

Nims RJ, Durney KM, Cigan AD, Dusseaux A, Hung CT, Ateshian GA., 2015. Damage mechanics in tissue engineered cartilage: biochemical data and computational models. Columbia University Academic Commons, http://dx.doi.org/10.7916/D8MP52JD.

Oungoulian SR, Durney KM, Jones BK, Ahmad CS, Hung CT, Ateshian GA., 2015. Wear and damage of articular cartilage with friction against orthopedic implant materials. J. Biomech. 48(10):1957-64.

Lima EG, Durney KM, Sirsi SR, Nover AB, Ateshian GA, Borden MA, Hung CT., 2012. Microbubbles as biocompatible porogens for hydrogel scaffolds. Acta Biomater. 8(12):4334-41.

Durney KM., 2011. Optimization of a Hydrogel Scaffold for Cartilage Tissue Engineering: Using Microbubbles to Mitigate Inhomogeneous Tissue Development. ProQuest UMI Dissertations Publishing 1489860.

Invited Conference Talks

Durney KM, Oungoulian SR, Jones BK, Suh JT, Hung CT, Ateshian GA., 2015. Cartilage wear initiated by fatigue damage under physiologic loading when fluid load support and boundary lubrication are compromised. Summer Biomechanics, Bioengineering and Biotransport Conference. Snowbird UT, USA.

Wang C, Durney KM, Fomovsky G, Ateshian GA, Vukelic S., 2015. Quantitative analysis of Raman spectra for assessment of collagen cross link concentrations for diagnosing osteoarthritis at early stages. Summer Biomechanics, Bioengineering and Biotransport Conference. Snowbird UT, USA.

Nims RJ, Cigan CD, Jones BK, Durney KM, Hung CT, Ateshian GA., 2015. A multigenerational collagen damage model explains engineered cartilage growth and remodeling phenomena. Summer Biomechanics, Bioengineering and Biotransport Conference. Snowbird UT, USA.

Albro MB, Durney KM, Shim JJ, Singh AJ, Ateshian GA, Stevens MM., 2015. Endogenous Stores of Latent TGF-β Serve to Maintain the Integrity and Viability of Articular Cartilage Over Long Term Culture in Response to Physiologic and Excessive Dynamic Mechanical Loading. Annual Meeting of the Orthopaedic Research Society. Las Vegas NV, USA.

Durney KM, Lima EG, Sirsi SR, Nover AB, Ateshian GA, Borden MA, Hung CT., 2011. Microbubbles Improve Depth-Dependent Mechanical Properties of Cartilage Tissue Engineered Constructs. Annual Meeting of the Orthopaedic Research Society. Long Beach CA, USA.

Lima EG, Durney KM, Sirsi SR, Nover AB, Ateshian GA, Borden MA, Hung CT., 2010. Using Microbubbles to Modulate Hydrogel Scaffold Properties for Cartilage Tissue Engineering. Annual Meeting of the Orthopaedic Research Society. New Orleans LA, USA.

Conference Abstracts

Durney KM, Nims RJ, Albro MB, Karbowski L, Singh AJ, Hung CT, Ateshian GA., 2015. Raman Spectrographic Characterization of Cartilage Matrix Swelling via Lysyl Oxidase Inhibition in Immature Explants and Tissue Constructs. Annual Meeting of the Orthopaedic Research Society. Las Vegas NV, USA.

Albro MB, Nims RJ, Durney KM, Cigan AD, Shim JJ, Vunjak-Novakovic G, Hung CT, Ateshian GA., 2015. Heterogeneous Growth of Engineered Cartilage Results From Gradients of Media Supplemented Active TGF-ß and is Ameliorated Through the Alternative Supplementation of Latent TGF-ß. Annual Meeting of the Orthopaedic Research Society. Las Vegas NV, USA.

Albro MB, Durney KM, Shim JJ, Cigan AD, Nims RJ, Hung CT, Ateshian GA., 2014. Endogenous stores of latent TGF-ß function to maintain the mechanical integrity of articular cartilage independent of physiologic mechanical loading: Assessment through the novel validation of the specificity of a small molecule TGF-ß inhibitor. Annual Meeting of the Orthopaedic Research Society. New Orleans LA, USA.

Albro MB, Durney KM, Shim JJ, Singh A, Nims RJ, Cigan AD, Hung CT, Ateshian GA., 2014. Synovial fluid and physiologic levels of cortisol, insulin, and glucose in media maintain the homeostasis of immature bovine cartilage explants over long-term culture. Annual Meeting of the Orthopaedic Research Society. New Orleans LA, USA.

Durney KM, Martinez R, Han HC., 2009. The Effect of Collagenase on Arterial Opening Angle. IEEE 35th Annual Northeast Bioengineering Conference. Cambridge MA, USA.

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